Human SNX19 activation kit by CRISPRa

CAT#: GA118262

SNX19 CRISPRa kit - CRISPR gene activation of human sorting nexin 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNX19
• Locus ID: 399979
• Kit Components:

  GA118262G1, SNX19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118262G2, SNX19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118262G3, SNX19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301089, NM_014758, NM_001347918, NM_001347919, NM_001347920, NM_001347921, NM_001347922, NM_001347923, NM_001347924, NM_001347925, NM_001347926, NM_001347927, NR_144939
• Synonyms: CHET8
• Summary: Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016]