Human CHCHD10 activation kit by CRISPRa

CAT#: GA118294

CHCHD10 CRISPRa kit - CRISPR gene activation of human coiled-coil-helix-coiled-coil-helix domain containing 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHCHD10
• Locus ID: 400916
• Kit Components:

  GA118294G1, CHCHD10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118294G2, CHCHD10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118294G3, CHCHD10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301339, NM_213720, NR_125755, NR_125756
• Synonyms: C22orf16; FTDALS2; IMMD; N27C7-4; SMAJ
• Summary: This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19. [provided by RefSeq, Aug 2014]