Human KPNA7 activation kit by CRISPRa

CAT#: GA118362

KPNA7 CRISPRa kit - CRISPR gene activation of human karyopherin subunit alpha 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KPNA7
• Locus ID: 402569
• Kit Components:

  GA118362G1, KPNA7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118362G2, KPNA7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118362G3, KPNA7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145715
• Synonyms: IPOA8
• Summary: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016]