Human TTDA (GTF2H5) activation kit by CRISPRa

CAT#: GA118391

GTF2H5 CRISPRa kit - CRISPR gene activation of human general transcription factor IIH subunit 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GTF2H5
• Locus ID: 404672
• Kit Components:

  GA118391G1, GTF2H5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118391G2, GTF2H5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118391G3, GTF2H5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_207118
• Synonyms: bA120J8.2; C6orf175; TFB5; TFIIH; TGF2H5; TTD; TTD-A; TTD3; TTDA
• Summary: This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]