Human CISD2 activation kit by CRISPRa

CAT#: GA118578

CISD2 CRISPRa kit - CRISPR gene activation of human CDGSH iron sulfur domain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CISD2
• Locus ID: 493856
• Kit Components:

  GA118578G1, CISD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118578G2, CISD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118578G3, CISD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008388
• Synonyms: ERIS; Miner1; NAF-1; WFS2; ZCD2
• Summary: The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]