Human SDHAF1 activation kit by CRISPRa

CAT#: GA118724

SDHAF1 CRISPRa kit - CRISPR gene activation of human succinate dehydrogenase complex assembly factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SDHAF1
• Locus ID: 644096
• Kit Components:

  GA118724G1, SDHAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118724G2, SDHAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118724G3, SDHAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042631
• Synonyms: LYRM8
• Summary: The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency). [provided by RefSeq, Mar 2010]