Human PET100 activation kit by CRISPRa

CAT#: GA119149

PET100 CRISPRa kit - CRISPR gene activation of human PET100 cytochrome c oxidase chaperone

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PET100
• Locus ID: 100131801
• Kit Components:

  GA119149G1, PET100 gRNA vector 1 in pCas-Guide-CRISPRa

  GA119149G2, PET100 gRNA vector 2 in pCas-Guide-CRISPRa

  GA119149G3, PET100 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171155, NR_033242
• Synonyms: C19orf79
• Summary: Mitochondrial complex IV, or cytochrome c oxidase, is a large transmembrane protein complex that is part of the respiratory electron transport chain of mitochondria. The small protein encoded by this gene plays a role in the biogenesis of mitochondrial complex IV. This protein localizes to the inner mitochondrial membrane and is exposed to the intermembrane space. Mutations in this gene are associated with mitochondrial complex IV deficiency. This gene has a pseudogene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]