Mouse Acox1 activation kit by CRISPRa

CAT#: GA200026

Acox1 CRISPRa kit - CRISPR gene activation of mouse acyl-Coenzyme A oxidase 1, palmitoyl


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Acox1
Locus ID 11430
Kit Components

GA200026G1, Acox1 gRNA vector 1 in pCas-Guide-CRISPRa

GA200026G2, Acox1 gRNA vector 2 in pCas-Guide-CRISPRa

GA200026G3, Acox1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001271898, NM_015729
Synonyms Acox; AOX; D130055E20Rik; Paox
Summary This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.