Mouse Acox1 activation kit by CRISPRa

CAT#: GA200026

Acox1 CRISPRa kit - CRISPR gene activation of mouse acyl-Coenzyme A oxidase 1, palmitoyl

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Acox1
• Locus ID: 11430
• Kit Components:

  GA200026G1, Acox1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200026G2, Acox1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200026G3, Acox1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271898, NM_015729
• Synonyms: Acox; AOX; D130055E20Rik; Paox
• Summary: This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]