Mouse Adam8 activation kit by CRISPRa

CAT#: GA200071

Adam8 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adam8
• Locus ID: 11501
• Kit Components:

  GA200071G1, Adam8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200071G2, Adam8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200071G3, Adam8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291066, NM_007403
• Synonyms: ADAM 8; CD156; CD156a; E430039A18Rik; MS2
• Summary: This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]