Mouse Adcyap1r1 activation kit by CRISPRa

CAT#: GA200079

Adcyap1r1 CRISPRa kit - CRISPR gene activation of mouse adenylate cyclase activating polypeptide 1 receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adcyap1r1
• Locus ID: 11517
• Kit Components:

  GA200079G1, Adcyap1r1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200079G2, Adcyap1r1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200079G3, Adcyap1r1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025372, NM_007407
• Synonyms: 2900024I10Rik; AI846590; PAC1; PAC1R; PACAP1-R
• Summary: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. [UniProtKB/Swiss-Prot Function]