Mouse Agrn activation kit by CRISPRa

CAT#: GA200122

Agrn CRISPRa kit - CRISPR gene activation of mouse agrin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Agrn
• Locus ID: 11603
• Kit Components:

  GA200122G1, Agrn gRNA vector 1 in pCas-Guide-CRISPRa

  GA200122G2, Agrn gRNA vector 2 in pCas-Guide-CRISPRa

  GA200122G3, Agrn gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021604, NM_001369026, NM_001369027
• Synonyms: Agrin; nmf380
• Summary: Agrin C-terminal 22 kDa fragment: this released fragment is important for agrin signaling and to exert a maximal dendritic filopodia-inducing effect. All 'z' splice variants (z+) of this fragment also show an increase in the number of filopodia. [UniProtKB/Swiss-Prot Function]