Mouse Ap2m1 activation kit by CRISPRa

CAT#: GA200212

Ap2m1 CRISPRa kit - CRISPR gene activation of mouse adaptor-related protein complex 2, mu 1 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ap2m1
• Locus ID: 11773
• Kit Components:

  GA200212G1, Ap2m1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200212G2, Ap2m1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200212G3, Ap2m1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302970, NM_009679
• Summary: This gene encodes the mu subunit of the clathrin adaptor protein complex AP-2. It mediates sorting of cargo proteins harboring Y-X-X-Phi motifs into clathrin-coated vesicles. Alternate splicing of this gene results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2, 8 and 19. [provided by RefSeq, Dec 2014]