Mouse Rab27a activation kit by CRISPRa

CAT#: GA200298

Rab27a CRISPRa kit - CRISPR gene activation of mouse RAB27A, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rab27a
• Locus ID: 11891
• Kit Components:

  GA200298G1, Rab27a gRNA vector 1 in pCas-Guide-CRISPRa

  GA200298G2, Rab27a gRNA vector 2 in pCas-Guide-CRISPRa

  GA200298G3, Rab27a gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301230, NM_001301232, NM_023635
• Synonyms: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash
• Summary: The protein encoded by this gene is a member of the Rab family of proteins, which is the largest family within the Ras superfamily of GTPases. This gene product is thought to regulate vesicular transport, together with its specific effectors. Mutations in this gene cause several defects, including actin-based melanosome transport defects and immunodeficiency. Mutations in the human ortholog of this gene are associated with Griscelli syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]