Mouse Bgn activation kit by CRISPRa

CAT#: GA200404

Bgn CRISPRa kit - CRISPR gene activation of mouse biglycan

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Bgn
• Locus ID: 12111
• Kit Components:

  GA200404G1, Bgn gRNA vector 1 in pCas-Guide-CRISPRa

  GA200404G2, Bgn gRNA vector 2 in pCas-Guide-CRISPRa

  GA200404G3, Bgn gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007542
• Synonyms: BG; DSPG1; PG-S1; PGI; SLRR1A
• Summary: This gene encodes a small, leucine-rich repeat proteoglycan that plays important roles in bone mineralization and connective tissue metabolism. The encoded preproprotein undergoes post-translational processing during which chondroitin sulfate or dermatan sulfate chains are attached before incorporation into the extracellular matrix. Mice lacking the encoded protein exhibit reduced growth rate and acquire diminished bone mass progressively with age. [provided by RefSeq, Oct 2015]