Mouse Serping1 activation kit by CRISPRa

CAT#: GA200458

Serping1 CRISPRa kit - CRISPR gene activation of mouse serine (or cysteine) peptidase inhibitor, clade G, member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Serping1
• Locus ID: 12258
• Kit Components:

  GA200458G1, Serping1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200458G2, Serping1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200458G3, Serping1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009776
• Synonyms: C1INH; C1nh
• Summary: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. May inhibit chymotrypsin and kallikrein. [UniProtKB/Swiss-Prot Function]