Mouse Calcr activation kit by CRISPRa

CAT#: GA200496

Calcr CRISPRa kit - CRISPR gene activation of mouse calcitonin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Calcr
• Locus ID: 12311
• Kit Components:

  GA200496G1, Calcr gRNA vector 1 in pCas-Guide-CRISPRa

  GA200496G2, Calcr gRNA vector 2 in pCas-Guide-CRISPRa

  GA200496G3, Calcr gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042725, NM_007588, NM_001355192
• Synonyms: Clr
• Summary: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. [UniProtKB/Swiss-Prot Function]