Mouse Calm1 activation kit by CRISPRa

CAT#: GA200497

Calm1 CRISPRa kit - CRISPR gene activation of mouse calmodulin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Calm1
• Locus ID: 12313
• Kit Components:

  GA200497G1, Calm1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200497G2, Calm1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200497G3, Calm1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313934, NM_009790
• Synonyms: AI256814; AI327027; AI461935; AL024000; Calm; CaM
• Summary: This gene encodes a member of the EF-hand calcium-binding protein family. The encoded protein acts as a calcium sensor and is involved in relaying signals to calcium-sensitive proteins, enzymes and ion channels. The protein-calcium complex binds target proteins to regulate several cellular processes, including smooth muscle contraction, inflammation, apoptosis and the immune response. Mutations in the human gene are associated with catecholaminergic polymorphic ventricular tachycardia and long QT syndrome 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]