Mouse Cap1 activation kit by CRISPRa

CAT#: GA200510

Cap1 CRISPRa kit - CRISPR gene activation of mouse CAP, adenylate cyclase-associated protein 1 (yeast)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cap1
• Locus ID: 12331
• Kit Components:

  GA200510G1, Cap1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200510G2, Cap1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200510G3, Cap1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301067, NM_007598, NM_001358035, NM_001358036
• Summary: The product of this gene plays a role in regulating actin dynamics by binding actin monomers and promoting the turnover of actin filaments. Reduced expression of this gene causes a reduction in actin filament turnover rates, causing multiple defects, including an increase in cell size, stress-fiber alterations, and defects in endocytosis and cell motility. A pseudogene of this gene is found on chromosome 14. Alternative splicing results in multiple transcript variants, but does not affect the protein. [provided by RefSeq, Jul 2014]