Mouse Capza1 activation kit by CRISPRa

CAT#: GA200519

Capza1 CRISPRa kit - CRISPR gene activation of mouse capping protein (actin filament) muscle Z-line, alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Capza1
• Locus ID: 12340
• Kit Components:

  GA200519G1, Capza1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200519G2, Capza1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200519G3, Capza1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009797, NM_001355044
• Synonyms: Cappa1; CAPZ; CAZ1
• Summary: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. [UniProtKB/Swiss-Prot Function]