Mouse Cav3 activation kit by CRISPRa

CAT#: GA200552

Cav3 CRISPRa kit - CRISPR gene activation of mouse caveolin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cav3
• Locus ID: 12391
• Kit Components:

  GA200552G1, Cav3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200552G2, Cav3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200552G3, Cav3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007617
• Synonyms: AI385751; Cav-3; M-cav
• Summary: This gene belongs to the caveolin family whose members encode the major protein components of caveolae, which are invaginations of plasma membrane. The encoded protein is muscle-specific and forms homooligomers in muscle cells. The protein binds and regulates phosphofructokinase M and neuronal nitric oxide synthase. It also associates with dystrophin in muscle cells. Mutations in this gene are associated with muscular dystrophy. [provided by RefSeq, Apr 2013]