Mouse Ctla4 activation kit by CRISPRa

CAT#: GA200602

Ctla4 CRISPRa kit - CRISPR gene activation of mouse cytotoxic T-lymphocyte-associated protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ctla4
• Locus ID: 12477
• Kit Components:

  GA200602G1, Ctla4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200602G2, Ctla4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200602G3, Ctla4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281976, NM_009843
• Synonyms: Cd152; Ctla-4; Ly-56
• Summary: This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]