Mouse Cd68 activation kit by CRISPRa

CAT#: GA200633

Cd68 CRISPRa kit - CRISPR gene activation of mouse CD68 antigen

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cd68
• Locus ID: 12514
• Kit Components:

  GA200633G1, Cd68 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200633G2, Cd68 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200633G3, Cd68 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291058, NM_009853, NR_110993
• Synonyms: gp110; Lamp4; Scard1
• Summary: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [UniProtKB/Swiss-Prot Function]