Mouse Cdh11 activation kit by CRISPRa

CAT#: GA200657

Cdh11 CRISPRa kit - CRISPR gene activation of mouse cadherin 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh11
• Locus ID: 12552
• Kit Components:

  GA200657G1, Cdh11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200657G2, Cdh11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200657G3, Cdh11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009866
• Synonyms: Cad11; OSF-4
• Summary: This gene encodes a type II classical cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]