Mouse Cdh13 activation kit by CRISPRa

CAT#: GA200658

Cdh13 CRISPRa kit - CRISPR gene activation of mouse cadherin 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh13
• Locus ID: 12554
• Kit Components:

  GA200658G1, Cdh13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200658G2, Cdh13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200658G3, Cdh13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019707
• Synonyms: 4932416G01Rik; Cdht; Tcad
• Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. This gene is highly expressed in the vasculature including endothelial cells, smooth muscle cells and pericytes, where the encoded protein binds to adiponectin and has been implicated in the modulation of angiogenesis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Nov 2015]