Mouse Cdh3 activation kit by CRISPRa

CAT#: GA200663

Cdh3 CRISPRa kit - CRISPR gene activation of mouse cadherin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh3
• Locus ID: 12560
• Kit Components:

  GA200663G1, Cdh3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200663G2, Cdh3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200663G3, Cdh3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037809, NM_007665
• Synonyms: AI385538; Cadp; Cdhp; P-cadherin; Pcad
• Summary: This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]