Mouse Cdh5 activation kit by CRISPRa

CAT#: GA200665

Cdh5 CRISPRa kit - CRISPR gene activation of mouse cadherin 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh5
• Locus ID: 12562
• Kit Components:

  GA200665G1, Cdh5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200665G2, Cdh5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200665G3, Cdh5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009868
• Synonyms: 7B4; AA408225; Cd144; VE-Cad; Vec; VEcad; VECD
• Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Oct 2015]