Mouse Cdh8 activation kit by CRISPRa

CAT#: GA200667

Cdh8 CRISPRa kit - CRISPR gene activation of mouse cadherin 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh8
• Locus ID: 12564
• Kit Components:

  GA200667G1, Cdh8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200667G2, Cdh8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200667G3, Cdh8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039154, NM_001285913, NM_001285914, NM_007667, NR_133570
• Synonyms: AI851472; cad8
• Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein exhibit reduced behavioral responses to cold, but not thermal stimuli. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Oct 2015]