Mouse Ces1g activation kit by CRISPRa

CAT#: GA200700

Ces1g CRISPRa kit - CRISPR gene activation of mouse carboxylesterase 1G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ces1g
• Locus ID: 12623
• Kit Components:

  GA200700G1, Ces1g gRNA vector 1 in pCas-Guide-CRISPRa

  GA200700G2, Ces1g gRNA vector 2 in pCas-Guide-CRISPRa

  GA200700G3, Ces1g gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021456
• Synonyms: Ces-1; Ces1; Ses-1
• Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8. [provided by RefSeq, Jun 2010]