Mouse Cfi activation kit by CRISPRa

CAT#: GA200704

Cfi CRISPRa kit - CRISPR gene activation of mouse complement component factor i

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cfi
• Locus ID: 12630
• Kit Components:

  GA200704G1, Cfi gRNA vector 1 in pCas-Guide-CRISPRa

  GA200704G2, Cfi gRNA vector 2 in pCas-Guide-CRISPRa

  GA200704G3, Cfi gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329552, NM_007686
• Summary: This gene encodes a serine protease that plays an important role in the classical and alternative complement pathways where it cleaves C4b and C3b components of C3 and C5 convertases. The encoded preproprotein undergoes proteolytic processing to generate an active, disulfide-linked heterodimeric enzyme comprised of heavy and light chains. [provided by RefSeq, Jul 2016]