Mouse Chrm1 activation kit by CRISPRa

CAT#: GA200724

Chrm1 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, muscarinic 1, CNS


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Chrm1
Locus ID 12669
Kit Components

GA200724G1, Chrm1 gRNA vector 1 in pCas-Guide-CRISPRa

GA200724G2, Chrm1 gRNA vector 2 in pCas-Guide-CRISPRa

GA200724G3, Chrm1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001112697, NM_007698
Synonyms Chrm-1; M1; M1R
Summary The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.