Mouse Chrm3 activation kit by CRISPRa

CAT#: GA200725

Chrm3 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, muscarinic 3, cardiac

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Chrm3
• Locus ID: 12671
• Kit Components:

  GA200725G1, Chrm3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200725G2, Chrm3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200725G3, Chrm3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033269
• Synonyms: Chrm-3; M3; M3R
• Summary: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. [UniProtKB/Swiss-Prot Function]