Mouse Camp activation kit by CRISPRa

CAT#: GA200789

Camp CRISPRa kit - CRISPR gene activation of mouse cathelicidin antimicrobial peptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Camp
• Locus ID: 12796
• Kit Components:

  GA200789G1, Camp gRNA vector 1 in pCas-Guide-CRISPRa

  GA200789G2, Camp gRNA vector 2 in pCas-Guide-CRISPRa

  GA200789G3, Camp gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009921
• Synonyms: CAP18; Cnlp; Cramp; FALL39; MCLP
• Summary: This gene encodes a member of the cathelicidin family of antimicrobial peptides that play an important role in the defense against microbial infection. The encoded preproprotein undergoes proteolytic processing to generate a mature polypeptide before secretion by host cells such as neutrophils, epithelial cells and macrophages. Mice lacking the encoded protein exhibit increased susceptibility to group A streptococcus and Escherichia coli infections. [provided by RefSeq, Oct 2015]