Mouse Col11a1 activation kit by CRISPRa

CAT#: GA200803

Col11a1 CRISPRa kit - CRISPR gene activation of mouse collagen, type XI, alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Col11a1
• Locus ID: 12814
• Kit Components:

  GA200803G1, Col11a1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200803G2, Col11a1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200803G3, Col11a1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007729
• Synonyms: C530001D20Rik; cho
• Summary: This gene encodes the alpha-1 subunit of type XI collagen, one of the low abundance fibrillar collagens that is essential for normal embryonic skeletal development and the cohesive properties of cartilage. The encoded protein, in association with the alpha-1 subunit of type II collagen, forms a heterotrimeric type XI procollagen that undergoes proteolytic processing. Mice lacking the encoded protein develop severe chondrodysplasia and die at birth. [provided by RefSeq, Dec 2015]