Mouse Comt activation kit by CRISPRa

CAT#: GA200832

Comt CRISPRa kit - CRISPR gene activation of mouse catechol-O-methyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Comt
• Locus ID: 12846
• Kit Components:

  GA200832G1, Comt gRNA vector 1 in pCas-Guide-CRISPRa

  GA200832G2, Comt gRNA vector 2 in pCas-Guide-CRISPRa

  GA200832G3, Comt gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001111062, NM_001111063, NM_007744
• Synonyms: Comt1; D16Wsu103e; D330014B15Rik
• Summary: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. [UniProtKB/Swiss-Prot Function]