Mouse Crem activation kit by CRISPRa

CAT#: GA200870

Crem CRISPRa kit - CRISPR gene activation of mouse cAMP responsive element modulator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Crem
• Locus ID: 12916
• Kit Components:

  GA200870G1, Crem gRNA vector 1 in pCas-Guide-CRISPRa

  GA200870G2, Crem gRNA vector 2 in pCas-Guide-CRISPRa

  GA200870G3, Crem gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001110850, NM_001110851, NM_001110852, NM_001110853, NM_001110854, NM_001110855, NM_001110856, NM_001110857, NM_001110858, NM_001110859, NM_001271503, NM_001271504, NM_001271505, NM_001271506, NM_001311066, NM_001311067, NM_013498, NR_073193
• Synonyms: ICER; ICERI
• Summary: This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]