Mouse Ctsk activation kit by CRISPRa

CAT#: GA200952

Ctsk CRISPRa kit - CRISPR gene activation of mouse cathepsin K

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ctsk
• Locus ID: 13038
• Kit Components:

  GA200952G1, Ctsk gRNA vector 1 in pCas-Guide-CRISPRa

  GA200952G2, Ctsk gRNA vector 2 in pCas-Guide-CRISPRa

  GA200952G3, Ctsk gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007802
• Synonyms: AI323530; catK; MMS10-Q; Ms10q
• Summary: This gene encodes a member of the cathepsin family of cysteine proteases that is highly expressed in osteoclasts and is involved in the degradation of collagen and other matrix proteins in bone. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme. Mice lacking the encoded protein exhibit phenotypic features of pycnodysostosis such as increased bone density and bone deformity, which become progressively more pronounced with age. [provided by RefSeq, Jan 2016]