Mouse Dazl activation kit by CRISPRa

CAT#: GA201019

Dazl CRISPRa kit - CRISPR gene activation of mouse deleted in azoospermia-like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dazl
• Locus ID: 13164
• Kit Components:

  GA201019G1, Dazl gRNA vector 1 in pCas-Guide-CRISPRa

  GA201019G2, Dazl gRNA vector 2 in pCas-Guide-CRISPRa

  GA201019G3, Dazl gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277863, NM_010021
• Synonyms: Daz-like; Dazh; Dazl1; Dazla; Tpx-2; Tpx2
• Summary: This gene encodes a member of the depleted in azoospermia-like (DAZL) protein family. Members of this family contain an RNA recognition motif, interact with poly A binding proteins, and may be involved in the initiation of translation. The encoded protein is expressed in the cytoplasm of pluripotent stem cells, and in both male and female germ cells, where it is essential for gametogenesis. Disruption of this gene is associated with infertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]