Mouse Dbi activation kit by CRISPRa

CAT#: GA201021

Dbi CRISPRa kit - CRISPR gene activation of mouse diazepam binding inhibitor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dbi
• Locus ID: 13167
• Kit Components:

  GA201021G1, Dbi gRNA vector 1 in pCas-Guide-CRISPRa

  GA201021G2, Dbi gRNA vector 2 in pCas-Guide-CRISPRa

  GA201021G3, Dbi gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037999, NM_007830
• Synonyms: ACBD1; Acbp; endozepine; EP
• Summary: Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. [UniProtKB/Swiss-Prot Function]