Mouse Dnm1 activation kit by CRISPRa

CAT#: GA201105

Dnm1 CRISPRa kit - CRISPR gene activation of mouse dynamin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dnm1
• Locus ID: 13429
• Kit Components:

  GA201105G1, Dnm1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201105G2, Dnm1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201105G3, Dnm1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301737, NM_010065, NR_125959, NM_001368679
• Synonyms: AI838169; Dnm; Ftfl; mKIAA4093
• Summary: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein is a GTPase which is required for membrane recycling, including vesicle endocytosis in neurons. It may also be involved in cellular fission via association with microtubules and actin filaments. Mutations in this gene have been shown to cause seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]