Mouse Adam28 activation kit by CRISPRa

CAT#: GA201143

Adam28 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 28

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adam28
• Locus ID: 13522
• Kit Components:

  GA201143G1, Adam28 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201143G2, Adam28 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201143G3, Adam28 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001048175, NM_010082, NM_176991, NM_183366, NR_102399
• Synonyms: C130072N01Rik; D430033C21Rik; Dtgn1; eMDCII; MDC-L; MDCL; TECADAM
• Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are typically membrane-anchored, although a form of this protein may be secreted. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a mature protein product. This protein may bind to integrins and regulate lymphocyte migration by enhancing cell adhesion. [provided by RefSeq, Aug 2015]