Mouse Ebp activation kit by CRISPRa

CAT#: GA201166

Ebp CRISPRa kit - CRISPR gene activation of mouse phenylalkylamine Ca2+ antagonist (emopamil) binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ebp
• Locus ID: 13595
• Kit Components:

  GA201166G1, Ebp gRNA vector 1 in pCas-Guide-CRISPRa

  GA201166G2, Ebp gRNA vector 2 in pCas-Guide-CRISPRa

  GA201166G3, Ebp gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007898
• Synonyms: AI255399; mSI; Pabp; SI; Td
• Summary: This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum. This protein catalyses the conversion of delta8 to delta7 sterols, an important step in sterol biosynthesis. Mutations in this gene are responsible for the mouse tattered mutant phenotype. Tattered males are embryonic lethal, while heterozygous females have developmental defects. Deficiency of the related gene in human causes X-linked dominant chondrodysplasia punctata. [provided by RefSeq, May 2015]