Mouse S1pr4 activation kit by CRISPRa

CAT#: GA201176

S1pr4 CRISPRa kit - CRISPR gene activation of mouse sphingosine-1-phosphate receptor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: S1pr4
• Locus ID: 13611
• Kit Components:

  GA201176G1, S1pr4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201176G2, S1pr4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201176G3, S1pr4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010102
• Synonyms: Edg6; Lpc1; S1p4
• Summary: This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for the lysophospholipid sphingosine 1-phosphate. The encoded protein is one of the predominant sphingosine 1-phosphate G-protein coupled receptors expressed in T cells, and it plays a role in suppression of T cell proliferation, generation of cytokines, and potentially other aspects of immune activation. [provided by RefSeq, Feb 2010]