Mouse Eef2 activation kit by CRISPRa

CAT#: GA201187

Eef2 CRISPRa kit - CRISPR gene activation of mouse eukaryotic translation elongation factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Eef2
• Locus ID: 13629
• Kit Components:

  GA201187G1, Eef2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201187G2, Eef2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201187G3, Eef2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007907
• Synonyms: Ef-2
• Summary: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. [UniProtKB/Swiss-Prot Function]