Mouse Ezh1 activation kit by CRISPRa

CAT#: GA201329

Ezh1 CRISPRa kit - CRISPR gene activation of mouse enhancer of zeste 1 polycomb repressive complex 2 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ezh1
• Locus ID: 14055
• Kit Components:

  GA201329G1, Ezh1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201329G2, Ezh1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201329G3, Ezh1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007970
• Synonyms: ENX-2
• Summary: This gene encodes a member of the Polycomb-group (PcG) family. The encoded protein is interchangeable with the related Enhancer of zeste 2 (Ezh2) protein as a core component of the polycomb repressive complex 2 (PRC2), which methylates histone H3 at lysine 27 and results in the transcriptional repression of affected target genes. This complex is involved in carrying out cell-fate decisions during embryonic stem cell differentiation. [provided by RefSeq, Sep 2014]