Mouse Fkbp5 activation kit by CRISPRa

CAT#: GA201430

Fkbp5 CRISPRa kit - CRISPR gene activation of mouse FK506 binding protein 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fkbp5
• Locus ID: 14229
• Kit Components:

  GA201430G1, Fkbp5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201430G2, Fkbp5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201430G3, Fkbp5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010220
• Synonyms: D17Ertd592e; Dit1; FKBP-5; FKBP51
• Summary: Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. [UniProtKB/Swiss-Prot Function]