Mouse Gdi1 activation kit by CRISPRa

CAT#: GA201585

Gdi1 CRISPRa kit - CRISPR gene activation of mouse guanosine diphosphate (GDP) dissociation inhibitor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Gdi1
• Locus ID: 14567
• Kit Components:

  GA201585G1, Gdi1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201585G2, Gdi1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201585G3, Gdi1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010273
• Synonyms: GDIA; GDIalpha
• Summary: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. [UniProtKB/Swiss-Prot Function]