Mouse Ggta1 activation kit by CRISPRa

CAT#: GA201601

Ggta1 CRISPRa kit - CRISPR gene activation of mouse glycoprotein galactosyltransferase alpha 1, 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ggta1
• Locus ID: 14594
• Kit Components:

  GA201601G1, Ggta1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201601G2, Ggta1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201601G3, Ggta1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145821, NM_001308299, NM_001308300, NM_010283
• Synonyms: alpha3GalT; alpha Gal; AW108479; Gal; GALT; Ggta; Ggta-1
• Summary: This gene encodes a member of the galactosyltransferase family of intracellular, membrane-bound enzymes that are involved in the biosynthesis of glycoproteins and glycolipids. The encoded protein catalyzes the transfer of galactose from UDP-galactose to N-acetyllactosamine in an alpha(1,3) linkage to form galactose alpha(1,3)-galactose. Mice lacking the encoded protein develop cortical cataracts. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2015]