Mouse B4galt1 activation kit by CRISPRa

CAT#: GA201602

B4galt1 CRISPRa kit - CRISPR gene activation of mouse UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B4galt1
• Locus ID: 14595
• Kit Components:

  GA201602G1, B4galt1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201602G2, B4galt1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201602G3, B4galt1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022305
• Synonyms: 4-GalT; 4-GalT1; B-1; b4Gal-T1; beta-1; beta4Gal-T1; GalT; Ggtb; Ggtb2
• Summary: This gene encodes two distinct enzyme isoforms, a long membrane-bound form and a short soluble form. These alternate isoforms are thought to be produced through alternative nested transcription initiation and different in-frame start codon usage. These enzymes catalyze the transfer of galactose to acceptor sugars, such as N-acetylglucosamine and glucose. The long form of this enzyme is localized to the trans-Golgi membrane and is involved in glycoconjugate biosynthesis. The short form functions in lactose biosynthesis though formation of a heterodimer with alpha-lactalbumin. [provided by RefSeq, Nov 2012]