Mouse Gjb1 activation kit by CRISPRa

CAT#: GA201618

Gjb1 CRISPRa kit - CRISPR gene activation of mouse gap junction protein, beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Gjb1
• Locus ID: 14618
• Kit Components:

  GA201618G1, Gjb1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201618G2, Gjb1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201618G3, Gjb1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302496, NM_001302497, NM_001302498, NM_008124
• Synonyms: Cnx32; connexin-32; Cx32
• Summary: This gene is a member of the gap junction protein (connexin) family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of ions and small molecules between cells. Mutations in a similar gene in human cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Oct 2014]