Mouse Grik1 activation kit by CRISPRa
CAT#: GA201736
Grik1 CRISPRa kit - CRISPR gene activation of mouse glutamate receptor, ionotropic, kainate 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Grik1 |
Locus ID | 14805 |
Kit Components | GA201736G1, Grik1 gRNA vector 1 in pCas-Guide-CRISPRa GA201736G2, Grik1 gRNA vector 2 in pCas-Guide-CRISPRa GA201736G3, Grik1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001346964, NM_010348, NM_146072 |
Synonyms | A830007B11Rik; D16Ium24; D16Ium24e; GluK1; GluK5; Glur-5; Glur5; Glurbeta1 |
Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN507324 | Grik1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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